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Pharmaceutical powder compaction technology / edited by Göran Alderborn, Christer Nyström. - New York : Marcel Dekker, c1996. - xv, 610 p. : ill. ; 23 cm. - Drugs and the pharmaceutical sciences. .

Includes bibliographical references and index.

I. Interparticulate bonding characteristics of pharmaceutical compacts --
1. Interparticulate attraction mechanisms --
2. The importance of intermolecular bonding forces and the concept of bonding surface area --
II. Characterization of the compression process --
3. Porosity-pressure functions --
4. Force-displacement and network measurements --
5. Viscoelastic models --
6. Application of percolation theory and fractal geometry to tablet compaction --
III. Characterization of compact properties --
7. Mechanical strength --
8. Tablet surface area --
9. Rationale for and the measurement of tableting indices --
IV. Material properties of importance for powder volume reduction and compact strength --
10. Particle dimensions --
11. Mechanical properties --
12. Granule properties --
13. Modeling the compression behavior of particle assemblies from the mechanical properties of individual particles --
V. Compaction properties of excipients and powder mixtures --
14. Materials for direct compaction --
15. Compaction properties of binary mixtures --
16. Lubricant sensitivity --
17. The development and optimization of tablet formulations using mathematical methods. TOC



ISBN: 0824793765 (alk. paper) 9780824793760

LCCN: 95024571

Subjects--Topical Terms:
Tablets (Medicine)

Subjects--Index Terms: Technology, Pharmaceutical.

LC Class. No.: RS201.T2 / P465 1996

Dewey Class. No.: 615.19 / PHA 1996