Pharmaceutical powder compaction technology /
edited by Göran Alderborn, Christer Nyström.
- New York : Marcel Dekker, c1996.
- xv, 610 p. : ill. ; 23 cm.
- Drugs and the pharmaceutical sciences. .
Includes bibliographical references and index.
I. Interparticulate bonding characteristics of pharmaceutical compacts --
1. Interparticulate attraction mechanisms --
2. The importance of intermolecular bonding forces and the concept of bonding surface area --
II. Characterization of the compression process --
3. Porosity-pressure functions --
4. Force-displacement and network measurements --
5. Viscoelastic models --
6. Application of percolation theory and fractal geometry to tablet compaction --
III. Characterization of compact properties --
7. Mechanical strength --
8. Tablet surface area --
9. Rationale for and the measurement of tableting indices --
IV. Material properties of importance for powder volume reduction and compact strength --
10. Particle dimensions --
11. Mechanical properties --
12. Granule properties --
13. Modeling the compression behavior of particle assemblies from the mechanical properties of individual particles --
V. Compaction properties of excipients and powder mixtures --
14. Materials for direct compaction --
15. Compaction properties of binary mixtures --
16. Lubricant sensitivity --
17. The development and optimization of tablet formulations using mathematical methods. Table of contents
0824793765 (alk. paper) 9780824793760
95024571
Tablets (Medicine)
Technology, Pharmaceutical.
RS201.T2 / P465 1996
615.19 / PHA 1996
Includes bibliographical references and index.
I. Interparticulate bonding characteristics of pharmaceutical compacts --
1. Interparticulate attraction mechanisms --
2. The importance of intermolecular bonding forces and the concept of bonding surface area --
II. Characterization of the compression process --
3. Porosity-pressure functions --
4. Force-displacement and network measurements --
5. Viscoelastic models --
6. Application of percolation theory and fractal geometry to tablet compaction --
III. Characterization of compact properties --
7. Mechanical strength --
8. Tablet surface area --
9. Rationale for and the measurement of tableting indices --
IV. Material properties of importance for powder volume reduction and compact strength --
10. Particle dimensions --
11. Mechanical properties --
12. Granule properties --
13. Modeling the compression behavior of particle assemblies from the mechanical properties of individual particles --
V. Compaction properties of excipients and powder mixtures --
14. Materials for direct compaction --
15. Compaction properties of binary mixtures --
16. Lubricant sensitivity --
17. The development and optimization of tablet formulations using mathematical methods. Table of contents
0824793765 (alk. paper) 9780824793760
95024571
Tablets (Medicine)
Technology, Pharmaceutical.
RS201.T2 / P465 1996
615.19 / PHA 1996