Bolton, Sanford.

Pharmaceutical statistics : practical and clinical applications / Sanford Bolton, Charles Bon. - 4th ed rev. and expanded. - New York : India : M. Dekker ; Replika Press Pvt. Ltd., c2004. - xiii, 755 p. : ill. ; 26 cm. + - Drugs and the pharmaceutical sciences ; 135. .

Includes bibliographical references and index.

1. Basic Definitions and Concepts --
2. Data Graphics --
3. Introduction to Probability: The Binomial and Normal Probability Distributions --
4. Choosing Samples --
5. Statistical Inference: Estimation and Hypothesis Testing --
6. Sample Size and Power --
7. Linear Regression and Correlation --
8. Analysis of Variance --
9. Factorial Designs --
10. Transformations and Outliers --
11. Experimental Design in Clinical Trials --
12. Quality Control --
13. Validation --
14. Computer Intensive Methods --
15. Nonparametric Methods --
16. Optimization Techniques and Screening Designs --
App. I. Some Properties of the Variance --
App. II. Comparison of Slopes and Testing of Linearity: Determination of Relative Potency --
App. III. Multiple Regression --
App. V. Outlier Tests and Chemical Assays --
App. VI. Should a Single Unexplained Failing Assay Be Reason to Reject a Batch? --
App. VII. When it is Appropriate to Average and its Relationship to the Barr Decision Table of contents

Summary:
The fourth edition of this text includes a disk with special programs to aid in problem analysis. The text presents fresh material on concept conformity and release targets and describes linear regression and correlation, the analysis of variance and crossover designs.



0824746953 (alk. paper) 9780824746957

2003066761


Pharmacy--Statistical methods.
Pharmacy--Laboratory Manuals.
Statistics--Laboratory Manuals.

RS57 / .B65 2004

615.1072 / BOP 2005

W1 / DR893B v.135 2004 QV 25 / B694p 2004

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