MARC details
| 000 -LEADER |
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| fixed length control field |
08497cam a22004214a 4500 |
| 001 - CONTROL NUMBER |
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| control field |
7047 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
BD-DhEWU |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20190214111150.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
120930s2010 enka g b 001 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9780470741856 (hardcover) |
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| International Standard Book Number |
9780470741849 (softcover) |
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| International Standard Book Number |
0470741848 |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
(OCoLC)495597806 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
DLC |
| Transcribing agency |
DLC |
| Modifying agency |
DLC |
| -- |
BD-DhEWU |
| Language of cataloging |
eng |
| 041 ## - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
eng |
| 050 00 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QH434 |
| Item number |
.D35 2010 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
572.8293 |
| Item number |
DAM 2010 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Dale, Jeremy, |
| Fuller form of name |
(Jeremy W.) |
| 9 (RLIN) |
7704 |
| 245 10 - TITLE STATEMENT |
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| Title |
Molecular genetics of bacteria / |
| Statement of responsibility, etc |
Jeremy W. Dale and Simon Park. |
| 250 ## - EDITION STATEMENT |
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| Edition statement |
5th ed. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Place of publication, distribution, etc |
Chichester, West Sussex, England ; |
| Name of publisher, distributor, etc |
Wiley-Blackwell, |
| Date of publication, distribution, etc |
c2010. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
xii, 388 p. : |
| Other physical details |
ill. ; |
| Dimensions |
25 cm. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc |
Includes bibliographical references (p. 333-335) and index. |
| 505 ## - FORMATTED CONTENTS NOTE |
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| Title |
TOC |
| Formatted contents note |
Preface. 1 Nucleic Acid Structure and Function. 1.1 Structure of nucleic acids. 1.1.1 DNA. 1.1.2 RNA. 1.1.3 Hydrophobic interactions. 1.1.4 Different forms of the double helix. 1.1.5 Supercoiling. 1.1.6 Denaturation and hybridization. 1.1.7 Orientation of nucleic acid strands. 1.2 Replication of DNA. 1.2.1 Unwinding and rewinding. 1.2.2 Fidelity of replication; proofreading. 1.3 Chromosome replication and cell division. 1.4 DNA repair. 1.4.1 Mismatch repair. 1.4.2 Excision repair. 1.4.3 Recombination (post-replication) repair. 1.4.4 SOS repair. 1.5 Gene expression. 1.5.1 Transcription. 1.5.2 Translation. 1.5.3 Post-translational events. 1.6 Gene organization. 2 Mutation and Variation. 2.1 Variation and evolution. 2.1.1 Fluctuation test. 2.1.2 Replica plating. 2.1.3 Directed mutation in bacteria? 2.2 Types of mutation. 2.2.1 Point mutations. 2.2.2 Conditional mutants. 2.2.3 Variation due to larger-scale DNA alterations. 2.2.4 Extrachromosomal agents and horizontal gene transfer. 2.3 Recombination. 2.3.1 A model of the general (homologous) recombination process. 2.3.2 Enzymes involved in recombination. 2.4 Phenotypes. 2.4.1 Restoration of phenotype. 2.5 Mechanisms of mutation. 2.5.1 Spontaneous mutation. 2.5.2 Chemical mutagens. 2.5.3 Ultraviolet irradiation. 2.6 Isolation and identification of mutants. 2.6.1 Mutation and selection. 2.6.2 Replica plating. 2.6.3 Isolation of other mutants. 2.6.4 Molecular methods. 3 Regulation of Gene Expression. 3.1 Gene copy number. 3.2 Transcriptional control. 3.2.1 Promoters. 3.2.2 Terminators, attenuators and anti-terminators. 3.2.3 Induction and repression: regulatory proteins. 3.2.4 Two-component regulatory systems. 3.2.5 Global regulatory systems. 3.2.6 Quorum sensing. 3.3 Translational control. 3.3.1 Ribosome binding. 3.3.2 Codon usage. 3.3.3 Stringent response. 3.3.4 Regulatory RNA. 3.4 Phase variation. 4 Genetics of Bacteriophages. 4.1 Bacteriophage structure. 4.2 Single-strand DNA bacteriophages. 4.2.1 X174. 4.2.2 M13. 4.3 RNA-containing phages: MS2. 4.4 Double-stranded DNA phages. 4.4.1 Bacteriophage T4. 4.4.2 Bacteriophage lambda. 4.4.3 Lytic and lysogenic regulation of bacteriophage lambda. 4.5 Restriction and modification. 4.6 Bacterial resistance to phage attack. 4.7 Complementation and recombination. 4.8 Why are bacteriophages important? 4.8.1 Phage typing. 4.8.2 Phage therapy. 4.8.3 Phage display. 4.8.4 Phages in the natural environment. 4.8.5 Bacterial virulence and phage conversion. 5 Plasmids. 5.1 Some bacterial characteristics are determined by plasmids. 5.1.1 Antibiotic resistance. 5.1.2 Colicins and bacteriocins. 5.1.3 Virulence determinants. 5.1.4 Plasmids in plant-associated bacteria. 5.1.5 Metabolic activities. 5.2 Molecular properties of plasmids. 5.2.1 Plasmid replication and control. 5.2.2 Partitioning. 5.2.3 Host range. 5.2.4 Plasmid incompatibility. 5.3 Plasmid stability. 5.3.1 Plasmid integrity. 5.3.2 Partitioning. 5.3.3 Differential growth rate. 5.4 Associating a plasmid with a phenotype. 6 Gene Transfer. 6.1 Transformation. 6.2 Conjugation. 6.2.1 Mechanism of conjugation. 6.2.2 The F plasmid. 6.2.3 Conjugation in other bacteria. 6.3 Transduction. 6.3.1 Specialized transduction. 6.4 Recombination. 6.4.1 Consequences of recombination. 6.4.2 Site-specific and non-homologous (illegitimate) recombination. 6.5 Mosaic genes and chromosome plasticity. 7 Genomic Plasticity: Movable Genes and Phase Variation. 7.1 Insertion sequences. 7.1.1 Structure of insertion sequences. 7.1.2 Occurrence of insertion sequences. 7.2 Transposons. 7.2.1 Structure of transposons. 7.2.2 Integrons. 7.2.3 IS CR elements. 7.3 Mechanisms of transposition. 7.3.1 Replicative transposition. 7.3.2 Non-replicative (conservative) transposition. 7.3.3 Regulation of transposition. 7.3.4 Activation of genes by transposable elements. 7.3.5 Mu: A transposable bacteriophage. 7.3.6 Conjugative transposons. 7.4 Phase variation. 7.4.1 Variation mediated by simple DNA inversion. 7.4.2 Variation mediated by nested DNA inversion. 7.4.3 Antigenic variation in the gonococcus. 7.4.4 Phase variation by slipped-strand mispairing. 7.4.5 Phase variation mediated by differential DNA methylation. 7.5 Clustered regularly interspersed short palindromic repeats. 8 Genetic Modification: Exploiting the Potential of Bacteria. 8.1 Strain development. 8.1.1 Generation of variation. 8.1.2 Selection of desired variants. 8.2 Overproduction of primary metabolites. 8.2.1 Simple pathways. 8.2.2 Branched pathways. 8.3 Overproduction of secondary metabolites. 8.4 Gene cloning. 8.4.1 Cutting and joining DNA. 8.4.2 Plasmid vectors. 8.4.3 Bacteriophage lambda vectors. 8.4.4 Cloning larger fragments. 8.4.5 Bacteriophage M13 vectors. 8.5 Gene libraries. 8.5.1 Construction of genomic libraries. 8.5.2 Screening a gene library. 8.5.3 Cloning PCR products. 8.5.4 Construction of a cDNA library. 8.6 Products from cloned genes. 8.6.1 Expression vectors. 8.6.2 Making new genes. 8.6.3 Other bacterial hosts. 8.6.4 Novel vaccines. 8.7 Other uses of gene technology. 9 Genetic Methods for Investigating Bacteria. 9.1 Metabolic pathways. 9.1.1 Complementation. 9.1.2 Cross-feeding. 9.2 Microbial physiology. 9.2.1 Reporter genes. 9.2.2 Chromatin immunoprecipitation. 9.2.3 Cell division. 9.2.4 Motility and chemotaxis. 9.2.5 Cell differentiation. 9.3 Bacterial virulence. 9.3.1 Wide-range mechanisms of bacterial pathogenesis. 9.3.2 Detection of virulence genes. 9.4 Specific mutagenesis. 9.4.1 Gene replacement. 9.4.2 Antisense RNA. 9.5 Taxonomy, evolution and epidemiology. 9.5.1 Molecular taxonomy. 9.5.2 GC content. 9.5.3 16 S rRNA. 9.5.4 Denaturing-gradient gel electrophoresis and temperature-gradient gel electrophoresis. 9.5.5 Diagnostic use of PCR. 9.5.6 Molecular epidemiology. 10 Gene Mapping to Genomics and Beyond. 10.1 Gene mapping. 10.1.1 Conjugational analysis. 10.1.2 Gene libraries. 10.1.3 Restriction mapping and pulsed-field gel electrophoresis. 10.2 DNA sequence determination. 10.2.1 Sanger sequencing. 10.2.2 Dye terminator sequencing. 10.2.3 Pyrosequencing. 10.2.4 Massively parallel sequencing. 10.3 Genome sequencing. 10.3.1 Genome-sequencing strategies. 10.3.2 Relating sequence to function. 10.3.3 Metagenomics. 10.4 Comparative genomics. 10.4.1 Microarrays. 10.5 Analysis of gene expression. 10.5.1 Transcriptional analysis. 10.5.2 Translational analysis. 10.6 Metabolomics. 10.7 Systems biology and synthetic genomics. 10.7.1 Systems biology. 10.7.2 Synthetic genomics. 10.8 Conclusion. Appendix A Further Reading. Appendix B Abbreviations Used. Appendix C Glossary. Appendix D Enzymes and other Proteins. Appendix E Genes. Appendix F Standard Genetic Code. Appendix G Bacterial Species. Index. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
This fifth edition provides students with an essential introduction to the molecular genetics of bacteria covering the basic concepts and the latest developments. It is comprehensive, easy to use and well structured with clear two-colour diagrams throughout. The focus of the book remains firmly on bacteria and will be invaluable to students studying microbiology, biotechnology, molecular biology, biochemistry, Read more... |
| 526 ## - STUDY PROGRAM INFORMATION NOTE |
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| Program name |
Pharmacy |
| -- |
GEB |
| 590 ## - LOCAL NOTE (RLIN) |
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| Local note |
Saifun Momota |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Bacterial genetics. |
| 9 (RLIN) |
7705 |
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| Topical term or geographic name as entry element |
Microbial genetics. |
| 9 (RLIN) |
7706 |
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| Topical term or geographic name as entry element |
Genetic engineering. |
| 9 (RLIN) |
7707 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Park, Simon, |
| Dates associated with a name |
1964- |
| 9 (RLIN) |
7708 |
| 856 42 - ELECTRONIC LOCATION AND ACCESS |
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| Materials specified |
WorldCat details |
| Uniform Resource Identifier |
http://www.worldcat.org/title/molecular-genetics-of-bacteria/oclc/495597806&referer=brief_results |
|
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| Materials specified |
E-book Fulltext |
| Uniform Resource Identifier |
http://lib.ewubd.edu/ebook/7047 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Text |
| Koha issues (borrowed), all copies |
3 |