Introduction to bioinformatics : a theoretical and practical approach / edited by Stephen A. Krawetz and David D. Womble.

Includes bibliographical references and index.

TOC Part I. Biochemistry, cell, and molecular biology: A. The Cell. Nucleic acids and proteins: modern linguistics for the genomics and bioinformatics era / Bradley C. Hyman --
Structure and function of cell organelles / Jon Holy --
Cell signaling / Daniel A. Rappolee --
B. Transcription and translatio. DNA replication, repair, and recombination / Linda B. Bloom --
Transcription, RNA processing, and translation / Thomas P. Yang and Thomas W. O'Brien --
Part II. Molecular genetics: A. Genomics. Epigenetic mechanisms regulating gene expression / John R. McCarrey --
Gene families and evolution / Ben F. Koop --
Repetitive DNA: detection, annotation, and analysis / Jerzy Jurka --
Molecular genetics of disease and the human genome project / Paromita Deb-Rinker and Stephen W. Scherer --
B. Clinical human genetics. Heredity / C.A. Rupar --
The clinical genetics databases / Peter J. Bridge --
Poulation genetics / Jill S. Barnholtz-Sloan. The UNIX operating system: A. Basics and installation. Introduction to UNIX for biologists / David D. Womble --
Installation of the sun solaris (TM) operating environment / Bryon Campbell --
Sun system administration / Bryon Campbell --
B. Managing bioinformatics tools. Installing bioinformatics software in a server-based computing environment / Brian Fristensky --
Management of a server-based bioinformatics resource / Brian Fristensky --
C. Command line sequence analysis. GCG file management / Sittichoke Saisanit --
Part IV. Computer applications: A. Management and alalysis of DNA sequencing projects and sequences. Managing sequencing projects in the GAP4 environment / Rodger Staden, David P. Judge, and James K. Bonfield --
OLIGO primer analysis software / John D. Offerman and Wojciech Rychlik --
Statistical modeling of DNA seuences and patterns / Gautam B. Singh --
Statistical mining of the matrix attachment regions in geonomic sequences / Gautam B. Singh --
Analyzing sequences using the Staden package and EMBOSS / Rodger Staden, David P. Judge, and James K. Bonfield --
B. The genome database: analysis and similarity searching. Ensembl: an open-source software tool for large-scale genome analysis / James W. Stalker and Anthony V. Cox --
The PIR for functional genomics and proteomics / Cathy H. Wu. Sequence similarity and database searching / David S. Wishart --
GCG database searching / David J. Heard --
C. Identifying functional and structural sequence elements. Pattern discovery: methods and software / Brona Brejova, Tomas Vinar, and Ming Li --
The role of transcription factor binding sites in promoters and their In Silico detection / Thomas Werner --
An introduction to multiple sequence alignment and analysis / Steven M. Thompson --
3D molecular visualization with protein explorer / Eric Martz --
Multiple sequence alignment and analysis: the Seqlab interface: a practical guide / Steven M. Thompson --
D. Analysis of gene expression: microarrays and other tools. Overview of the tools for microarray analysis: transcription profiling, DNA chips, and differential display / Jeffrey A. Kramer --
Microarays: tools for gene expression analysis / Sorin Draghici --
Knowledge discovery from the human transcriptome / Kousaku Okubo and Teruyoshi Hishiki.l.

Summary:
Offers scientists with both a biological framework to understand the questions life scientist confront in the context of the computational issues and tools that are available for scientific research. Read more...

APE

Saifun Momota