000 05266cam a22004454a 4500
001 5483
003 BD-DhEWU
005 20180206115109.0
008 041115s2005 njua g fb 001 0 eng d
010 _a 2004027077
020 _a0471213845 (cloth)
020 _a9780471213840
020 _a0471728772
020 _a9780471728771
035 _a(OCoLC)609350479
040 _aDLC
_cDLC
_dDLC
_dBD-DhEWU
_beng
041 _aeng
050 0 0 _aRM301.25
_b.D784 2005
082 0 4 _a615.19
_bDRU 2005
245 0 0 _aDrug discovery handbook /
_cedited by Shayne Cox Gad.
260 _aHoboken, N.J. :
_bWiley-Interscience,
_cc2005.
300 _axix, 1471 p. :
_bill. ;
_c25 cm.
504 _aIncludes bibliographical references and index.
505 0 _tTOC
_aDrug discovery in the 21st century: an introduction / Shayne C. Gad -- Natural products / Charles B. Spainhour -- Cancer cell proteomics using molecular aptamers / Weihong Tan, Zehui Cao, Dihua Shangguang -- Molecular similarity methods and QSAR models as tools for virtual screening / Jürgen Bajorath -- Systems biology: applications in drug discovery / Sean Ekins ...[et al.] -- High throughput flow cytometry / Larry A. Sklar ... [et al.] -- Combining NMR spectral information with associated structural features to form computationally non-intensive, rugged, and objective models of biological activity / Richard Beger, Dan A. Buzatu, Jon G. Wilkes -- Using Microsoft Excel as a laboratory data management tool / A. Erik Rubin, Mark F. Russo, William Neil -- The age of regulation / Sandy Weinberg, Gerald J. Whartenby -- Simultaneous screening of multiple cell lines using the CellCardtm system / Oren E. Beske -- Protein x-ray crystallography in drug discovery / Peter Nollert ...[et al.] -- Biological and chemistry assays available during drug discovery and developability assessment / Duane B. Lakings -- Strategies and methods in monitoring and targeting protein-protein interactions / Arianna Loregian, Giorgio Palù -- High throughput screening: evolution of technology and methods -- Martyn N. Banks ... [et al.] -- Metal-enhanced fluorescence: application to high-throughput screening and drug discovery / Kadir Aslan .. [et al,] -- Methods for the design and analysis of replicate-experiment studies to establish assay reproducibility and the equivalence of two potency assays / Brian J. Eastwood ... [et al.] -- Coupled luminescent methods in drug discovery: three-minute assays for cytotoxicity and phosphatase activity / Michael J. Corey, Robert J. Kinders -- Design and pharmaceutical applications of prodrugs / Tomi Jarvinen ... [et al.] -- GABA and glutamate receptor ligands and their therapeutic potential in CNS disorders / Ulf Madsen ... [et al.] -- Cardiac sarcolemmal ATP-sensitive potassium channel antagonists: novel ischemia-selective antiarrhythmic agents / George E. Billman -- Factors influencing the efficacy of mediator-specific anti-inflammatory, glucocorticoid and anti-coagulant therapies for sepsis / Peter C. Minneci ... [et al.] -- Combinatorial chemistry in the drug discovery process / Nathan T. Ross, Brian R. McNaughton, Benjamin L. Miller -- Herbal medicines and animal models of gastrointestinal diseases / C.H. Cho, J.K.S. Ko -- Endocrine and metabolic agents / Brian L. Furman -- Respiratory viruses / Paul D. Olivo -- Strategies in the design of antiviral drugs / Erik De Clercq, Piet Herdewijn -- Protein kinase inhibitors in drug discovery / Keykavous Parang, Gongqin Sun -- RNA-based therapies / Ingmar Hoerr, Steve Pascolo -- Novel imaging agents for molecular MR imaging of cancer / Dmitri Artemov, Zaver M. Bhujwalla -- Genomics-based drug discovery / Spyro Mousses -- Cancer drug discovery / Susan Mooberry.
520 _aThe Drug Discovery Handbook gives professionals a tool to facilitate drug discovery by bringing together, for the first time in one resource, a compendium of methods and techniques that need to be considered when developing new drugs.This comprehensive, practical guide presents an explanation of the latest techniques and methods in drug discovery, including: Genomics, proteomics, high-throughput screening, and systems biology Summaries of how these techniques and methods are used to discover new central nervous system agents, antiviral agents, respiratory drugs, oncology drugs, and more Specif.
526 _aPharmacy
590 _aSagar Shahanawaz
650 0 _aDrugs
_xResearch
_vHandbooks, manuals, etc.
_916491
650 0 _aDrug development
_vHandbooks, manuals, etc.
_916492
650 0 _aDrugs
_xDesign
_vHandbooks, manuals, etc.
_916493
650 0 _aPharmaceutical chemistry
_vHandbooks, manuals, etc.
_98804
700 1 _aGad, Shayne C.,
_d1948-
_916494
856 4 1 _3Table of contents only
_uhttp://www.loc.gov/catdir/toc/ecip053/2004027077.html
856 4 2 _3Contributor biographical information
_uhttp://www.loc.gov/catdir/enhancements/fy0617/2004027077-b.html
856 4 2 _3Publisher description
_uhttp://www.loc.gov/catdir/enhancements/fy0617/2004027077-d.html
856 4 2 _3WorldCat details
_uhttps://www.worldcat.org/title/drug-discovery-handbook/oclc/609350479&referer=brief_results
856 4 2 _3Ebook Fulltext
_uhttp://lib.ewubd.edu/ebook/5483
942 _2ddc
_cTEXT
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_d5483
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